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The Philadelphia chromosome: [a mutant gene and the quest to cure cancer at the genetic level]

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A Wall Street Journal 10 Best Nonfiction Book of the Year "Among a small cluster of very good recent books on cancer." -- The New York Times

Philadelphia, 1959: A scientist scrutinizing a single human cell under a microscope detects a missing piece of DNA. That scientist, David Hungerford, had no way of knowing that he had stumbled upon the starting point of modern cancer research-- the Philadelphia chromosome. It would take doctors and researchers around the world more than three decades to unravel the implications of this landmark discovery. In 1990, the Philadelphia chromosome was recognized as the sole cause of a deadly blood cancer, chronic myeloid leukemia, or CML. Cancer research would never be the same. Science journalist Jessica Wapner reconstructs more than forty years of crucial breakthroughs, clearly explains the science behind them, and pays tribute--with extensive original reporting, including more than thirty-five interviews--to the dozens of researchers, doctors, and patients with a direct role in this inspirational story. Their curiosity and determination would ultimately lead to a lifesaving treatment unlike anything before it. The Philadelphia Chromosome chronicles the remarkable change of fortune for the more than 70,000 people worldwide who are diagnosed with CML each year. It is a celebration of a rare triumph in the battle against cancer and a blueprint for future research, as doctors and scientists race to uncover and treat the genetic roots of a wide range of cancers.

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ISBN:
9781615190676
9781622311781
9781615191659
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Grouping Information

Grouped Work ID c0df6618-80ee-39c7-2485-0f58aed0cec7
Grouping Title philadelphia chromosome a mutant gene and the quest to cure cancer at the genetic level
Grouping Author wapner jessica
Grouping Category book
Last Grouping Update 2019-01-22 04:01:12AM
Last Indexed 2019-02-15 04:30:04AM

Solr Details

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accelerated_reader_point_value 0
accelerated_reader_reading_level 0
auth_author2 Henderson, Heather.
author Wapner, Jessica.
author2-role Henderson, Heather.|Narrator, HighBridge Audio (Firm), OneClick Digital (Firm), hoopla digital.
author_display Wapner, Jessica
available_at_boulder Boulder Main Library
detailed_location_boulder Boulder Main Adult NonFiction, Online Hoopla Collection
display_description Philadelphia, 1959: A scientist scrutinizing a single human cell under a microscope detects a missing piece of DNA. That scientist, David Hungerford, had no way of knowing that he had stumbled upon the starting point of modern cancer research- the Philadelphia chromosome. It would take doctors and researchers around the world more than three decades to unravel the implications of this landmark discovery. In 1990, the Philadelphia chromosome was recognized as the sole cause of a deadly blood cancer, chronic myeloid leukemia, or CML. Cancer research would never be the same. Science journalist Jessica Wapner reconstructs more than forty years of crucial breakthroughs, clearly explains the science behind them, and pays tribute-with extensive original reporting, including more than thirty-five interviews-to the dozens of researchers, doctors, and patients with a direct role in this inspirational story. Their curiosity and determination would ultimately lead to a lifesaving treatment unlike anything before it. The Philadelphia Chromosome chronicles the remarkable change of fortune for the more than 70,000 people worldwide who are diagnosed with CML each year. It is a celebration of a rare triumph in the battle against cancer and a blueprint for future research, as doctors and scientists race to uncover and treat the genetic roots of a wide range of cancers.
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last_indexed 2019-02-15T11:30:04.614Z
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local_callnumber_boulder 616.99419 Wapn
owning_library_boulder Boulder Public Library
owning_location_boulder Boulder Main Library
primary_isbn 9781615190676
publishDate 2013, 2014
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subject_facet Cancer -- Genetic aspects, Cancer -- Research, Chronic myeloid leukemia -- Genetic aspects, Chronic myeloid leukemia -- History, Downloadable audio books, Electronic books, Fusion Proteins, bcr-abl -- history -- United States, Genetic Therapy -- history -- United States, Hungerford, David S., -- 1938-, Imatinib, Leukemia, Myelogenous, Chronic, BCR-ABL Positive -- history -- United States, Mutation (Biology), Philadelphia Chromosome -- United States
title_display The Philadelphia chromosome : a mutant gene and the quest to cure cancer at the genetic level
title_full The Philadelphia chromosome : a mutant gene and the quest to cure cancer at the genetic level / Jessica Wapner ; foreword by Robert A. Weinberg, The Philadelphia chromosome : a mutant gene and the quest to cure cancer at the genetic level [electronic resource] / Jessica Wapner, The Philadelphia chromosome : a mutant gene and the quest to cure cancer at the genetic level [electronic resource] Wapner, Jessica., The Philadelphia chromosome [electronic resource] : [a mutant gene and the quest to cure cancer at the genetic level] / Jessica Wapner
title_short The Philadelphia chromosome :
title_sub [a mutant gene and the quest to cure cancer at the genetic level]
topic_facet Cancer, Chronic myeloid leukemia, Electronic books, Fusion Proteins, bcr-abl, Genetic Therapy, Genetic aspects, History, Hungerford, David S, Imatinib, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Mutation (Biology), Philadelphia Chromosome, Research, history